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实验室致力于结合独特模式体系、基因组学工具开发和定量建模，解析组织构建和信号传导中的物理化学过程，并探索其在再生、发育和癌症中的应用。& Q: W; |. F. @3 a
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我们好奇很多事情：发育生物学、RNA生物学、系统生物学、生物化学、统计物理学；也花时间动手搭建这些学科研究所需的高通量测序和高分辨率成像工具。
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[1] Fan Y, Chai C, Li P, Zou X, Ferrell JE, Wang B. (2023). Ultrafast distant wound response is essential for whole-body regeneration. Cell, 186, 3606-3618.
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1 R# [) [4 i3 g; C* P- H; k[2] Fan Y*, Andrusivova Z*, Wu Y, Chai C, Larsson L, He M, Luo L, Lundeberg J, Wang B. (2023). Expansion spatial transcriptomics. Nature Methods, 20, 1179-1182. (*= equal contribution)., V s' x$ w- r* s" V0 M
9 y8 q; W- L8 W2 D1 N. H% ?+ b8 [[3] Fan Y*, Lim Y*, Wyss L, Park S, Xu C, Fu H, Fei J, Hong Y, Wang B. (2021). Mechanical expansion microscopy. Methods in Cell Biology, 161, 125-146. (*= equal contribution).
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[4] Fan Y, Xiao Y, Momeni B, Liu Y. (2018). Horizontal gene transfer can help maintain the equilibrium of microbial communities. Journal of Theoretical Biology, 454, 53-59.7 H+ A& [* U( ^( b: g' p$ Y; O
/ c6 d) \0 o% [6 e: [[5] Fan Y, Cao G, He S, Chen J, Sun Y. (2017). Game among interdependent networks: The impact of rationality on system robustness. Europhysics Letters, 116, 68002.) _4 _9 @% [, p$ m$ d
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[6] Tian L, Wang X, Wu A, Fan Y, Friedman J, Waldor M, Weiss S, Liu Y. (2020). Deciphering functional redundancy in the Human Microbiome. Nature Communications, 11, 6217.# U6 k% r/ e4 g2 I& @( D$ q& U
9 Z8 w( Y# g* \4 Q$ p% T, i[7] Bray S, Fan Y, Wang B. (2019). Phase transitions in mutualistic communities under invasion. Physical Biology |
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